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Pre-fusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy

The activation of trimeric HIV-1 envelope glycoprotein (Env) by its binding to the cell surface receptor CD4 and co-receptors (CCR5 or CXCR4) represents the first of a series of events that lead to fusion between viral and target cell membranes. Here, we present the cryo-electron microscopic structu...

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Detalles Bibliográficos
Autores principales: Bartesaghi, Alberto, Merk, Alan, Borgnia, Mario J., Milne, Jacqueline L. S., Subramaniam, Sriram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917492/
https://www.ncbi.nlm.nih.gov/pubmed/24154805
http://dx.doi.org/10.1038/nsmb.2711

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