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Pre-fusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy
The activation of trimeric HIV-1 envelope glycoprotein (Env) by its binding to the cell surface receptor CD4 and co-receptors (CCR5 or CXCR4) represents the first of a series of events that lead to fusion between viral and target cell membranes. Here, we present the cryo-electron microscopic structu...
Autores principales: | Bartesaghi, Alberto, Merk, Alan, Borgnia, Mario J., Milne, Jacqueline L. S., Subramaniam, Sriram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917492/ https://www.ncbi.nlm.nih.gov/pubmed/24154805 http://dx.doi.org/10.1038/nsmb.2711 |
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