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Dabrafenib for treatment of BRAF-mutant melanoma

Melanoma has the highest mortality of all the skin cancer subtypes. Historically, chemotherapy and immunologic therapies have yielded only modest results in the treatment of metastatic melanoma. The discovery of prevalent V600 BRAF mutations driving proliferation makes this oncogenic protein an idea...

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Detalles Bibliográficos
Autores principales:	Kainthla, Radhika, Kim, Kevin B, Falchook, Gerald S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917541/ https://www.ncbi.nlm.nih.gov/pubmed/24516336 http://dx.doi.org/10.2147/PGPM.S37220

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