Orally delivered water soluble Coenzyme Q(10) (Ubisol-Q(10)) blocks on-going neurodegeneration in rats exposed to paraquat: potential for therapeutic application in Parkinson’s disease

BACKGROUND: Paraquat, still used as an herbicide in some parts of the world, is now regarded as a dangerous environmental neurotoxin and is linked to the development Parkinson’s disease (PD). Paraquat interacts with cellular redox systems and causes mitochondrial dysfunction and the formation of rea...

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Detalles Bibliográficos
Autores principales: Muthukumaran, Krithika, Leahy, Samantha, Harrison, Kate, Sikorska, Marianna, Sandhu, Jagdeep K, Cohen, Jerome, Keshan, Corrine, Lopatin, Daniel, Miller, Harvey, Borowy-Borowski, Henryk, Lanthier, Patricia, Weinstock, Shelly, Pandey, Siyaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917573/
https://www.ncbi.nlm.nih.gov/pubmed/24483602
http://dx.doi.org/10.1186/1471-2202-15-21

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