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RNA polymerase II termination involves CTD tyrosine dephosphorylation by CPF subunit Glc7

At the 3′ end of protein-coding genes, RNA polymerase (Pol) II is dephosphorylated at tyrosine (Tyr1) residues of its C-terminal domain (CTD). In addition, the associated cleavage and polyadenylation (pA) factor (CPF) cleaves the transcript and adds a polyA tail. Whether these events are coordinated...

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Detalles Bibliográficos
Autores principales: Schreieck, Amelie, Easter, Ashley D., Etzold, Stefanie, Wiederhold, Katrin, Lidschreiber, Michael, Cramer, Patrick, Passmore, Lori A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917824/
https://www.ncbi.nlm.nih.gov/pubmed/24413056
http://dx.doi.org/10.1038/nsmb.2753