TLR2, TLR4 and CD14 Recognize Venom-Associated Molecular Patterns from Tityus serrulatus to Induce Macrophage-Derived Inflammatory Mediators

Scorpion sting-induced human envenomation provokes an intense inflammatory reaction. However, the mechanisms behind the recognition of scorpion venom and the induction of mediator release in mammalian cells are unknown. We demonstrated that TLR2, TLR4 and CD14 receptors sense Tityus serrulatus venom...

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Detalles Bibliográficos
Autores principales: Zoccal, Karina Furlani, Bitencourt, Claudia da Silva, Paula-Silva, Francisco Wanderley Garcia, Sorgi, Carlos Artério, de Castro Figueiredo Bordon, Karla, Arantes, Eliane Candiani, Faccioli, Lúcia Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917877/
https://www.ncbi.nlm.nih.gov/pubmed/24516606
http://dx.doi.org/10.1371/journal.pone.0088174

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