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Decitabine in the treatment of acute myeloid leukemia in elderly patients

The majority of patients with acute myeloid leukemia (AML) are elderly and have a poor prognosis despite induction therapy. Decitabine, a DNA-hypomethylating agent that induces differentiation and apoptosis of leukemic cells, is a well-tolerated alternative to aggressive chemotherapy. It is currentl...

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Detalles Bibliográficos
Autores principales:	Malik, Priya, Cashen, Amanda F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917925/ https://www.ncbi.nlm.nih.gov/pubmed/24520204 http://dx.doi.org/10.2147/CMAR.S40600

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