Siah2 regulates tight junction integrity and cell polarity through control of ASPP2 stability

Changes in cell adhesion and polarity are closely associated with epithelial cell transformation and metastatic capacity. The tumor suppressor protein ASPP2 has been implicated in control of cell adhesion and polarity, through its effect on the PAR complex. Here we demonstrate that under hypoxic con...

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Detalles Bibliográficos
Autores principales: Kim, Hyungsoo, Claps, Guisepinna, Möller, Andreas, Bowtell, David, Lu, Xin, Ronai, Ze'ev A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917971/
https://www.ncbi.nlm.nih.gov/pubmed/23644657
http://dx.doi.org/10.1038/onc.2013.149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917971/
https://www.ncbi.nlm.nih.gov/pubmed/23644657
http://dx.doi.org/10.1038/onc.2013.149

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