The ginsenoside metabolite compound K, a novel agonist of glucocorticoid receptor, induces tolerance to endotoxin-induced lethal shock

Compound K (C-K), a protopanaxadiol ginsenoside metabolite, was previously shown to have immunomodulatory effects. Here, we describe a novel therapeutic role for C-K in the treatment of lethal sepsis through the modulation of Toll-like receptor (TLR) 4-associated signalling via glucocorticoid recept...

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Detalles Bibliográficos
Autores principales: Yang, Chul-Su, Ko, Sung-Ryong, Cho, Byung-Goo, Shin, Dong-Min, Yuk, Jae-Min, Li, Shengjin, Kim, Jin-Man, Evans, Ronald M, Jung, Jun-Sub, Song, Dong-Keun, Jo, Eun-Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918090/
https://www.ncbi.nlm.nih.gov/pubmed/18053081
http://dx.doi.org/10.1111/j.1582-4934.2007.00181.x

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