Is the inflammasome a potential therapeutic target in renal disease?

The inflammasome is a large, multiprotein complex that drives proinflammatory cytokine production in response to infection and tissue injury. Pattern recognition receptors that are either membrane bound or cytoplasmic trigger inflammasome assembly. These receptors sense danger signals including dama...

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Detalles Bibliográficos
Autores principales: Turner, Clare M, Arulkumaran, Nishkantha, Singer, Mervyn, Unwin, Robert J, Tam, Frederick WK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918225/
https://www.ncbi.nlm.nih.gov/pubmed/24450291
http://dx.doi.org/10.1186/1471-2369-15-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918225/
https://www.ncbi.nlm.nih.gov/pubmed/24450291
http://dx.doi.org/10.1186/1471-2369-15-21

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