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Dose KRAS Mutation Status Affect on the Effect of VEGF Therapy in Metastatic Colon Cancer Patients?
PURPOSE: Mutations affecting the KRAS gene are an established negative predictor for anti-epidermal growth factor receptor (anti-EGFR) therapies in metastatic colorectal cancer (CRC). However, the role of KRAS mutation as a biomarker for anti-vascular endothelial growth factor (VEGF) remains controv...
Autores principales: | Kim, Seung Tae, Park, Kyong Hwa, Shin, Sang Won, Kim, Yeul Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Cancer Association
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918527/ https://www.ncbi.nlm.nih.gov/pubmed/24520223 http://dx.doi.org/10.4143/crt.2014.46.1.48 |
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