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Function of YY1 in Long-Distance DNA Interactions
During B cell development, long-distance DNA interactions are needed for V(D)J somatic rearrangement of the immunoglobulin (Ig) loci to produce functional Ig genes, and for class switch recombination (CSR) needed for antibody maturation. The tissue-specificity and developmental timing of these mecha...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918653/ https://www.ncbi.nlm.nih.gov/pubmed/24575094 http://dx.doi.org/10.3389/fimmu.2014.00045 |