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Function of YY1 in Long-Distance DNA Interactions

During B cell development, long-distance DNA interactions are needed for V(D)J somatic rearrangement of the immunoglobulin (Ig) loci to produce functional Ig genes, and for class switch recombination (CSR) needed for antibody maturation. The tissue-specificity and developmental timing of these mecha...

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Detalles Bibliográficos
Autor principal: Atchison, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918653/
https://www.ncbi.nlm.nih.gov/pubmed/24575094
http://dx.doi.org/10.3389/fimmu.2014.00045