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V(H) Replacement Footprint Analyzer-I, a Java-Based Computer Program for Analyses of Immunoglobulin Heavy Chain Genes and Potential V(H) Replacement Products in Human and Mouse

V(H) replacement occurs through RAG-mediated secondary recombination between a rearranged V(H) gene and an upstream unrearranged V(H) gene. Due to the location of the cryptic recombination signal sequence (cRSS, TACTGTG) at the 3′ end of V(H) gene coding region, a short stretch of nucleotides from t...

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Detalles Bibliográficos
Autores principales: Huang, Lin, Lange, Miles D., Zhang, Zhixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918983/
https://www.ncbi.nlm.nih.gov/pubmed/24575092
http://dx.doi.org/10.3389/fimmu.2014.00040