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Rationale and study design of the Prospective comparison of Angiotensin Receptor neprilysin inhibitor with Angiotensin receptor blocker MEasuring arterial sTiffness in the eldERly (PARAMETER) study
INTRODUCTION: Hypertension in elderly people is characterised by elevated systolic blood pressure (SBP) and increased pulse pressure (PP), which indicate large artery ageing and stiffness. LCZ696, a first-in-class angiotensin receptor neprilysin inhibitor (ARNI), is being developed to treat hyperten...
Autores principales: | Williams, Bryan, Cockcroft, John R, Kario, Kazuomi, Zappe, Dion H, Cardenas, Pamela, Hester, Allen, Brunel, Patrick, Zhang, Jack |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918996/ https://www.ncbi.nlm.nih.gov/pubmed/24496699 http://dx.doi.org/10.1136/bmjopen-2013-004254 |
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