Cargando…

Studies on Emblica officinalis Derived Tannins for Their Immunostimulatory and Protective Activities against Coccidiosis in Industrial Broiler Chickens

The present study reports the effect of Emblica officinalis (EO) derived tannins on humoral immune responses and their protective efficacy against Eimeria infection in chickens. Tannins were extracted from EO and characterized by HPLC. EO derived tannins (EOT) and commercial tannins (CT) were orally...

Descripción completa

Detalles Bibliográficos
Autores principales: Kaleem, Qari Muhammad, Akhtar, Masood, Awais, Mian Muhammad, Saleem, Muhammad, Zafar, Muddassar, Iqbal, Zafar, Muhammad, Faqir, Anwar, Muhammad Irfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919087/
https://www.ncbi.nlm.nih.gov/pubmed/24578631
http://dx.doi.org/10.1155/2014/378473
_version_ 1782303018709942272
author Kaleem, Qari Muhammad
Akhtar, Masood
Awais, Mian Muhammad
Saleem, Muhammad
Zafar, Muddassar
Iqbal, Zafar
Muhammad, Faqir
Anwar, Muhammad Irfan
author_facet Kaleem, Qari Muhammad
Akhtar, Masood
Awais, Mian Muhammad
Saleem, Muhammad
Zafar, Muddassar
Iqbal, Zafar
Muhammad, Faqir
Anwar, Muhammad Irfan
author_sort Kaleem, Qari Muhammad
collection PubMed
description The present study reports the effect of Emblica officinalis (EO) derived tannins on humoral immune responses and their protective efficacy against Eimeria infection in chickens. Tannins were extracted from EO and characterized by HPLC. EO derived tannins (EOT) and commercial tannins (CT) were orally administered in broiler chicks in graded doses for three consecutive days, that is, 5th-7th days of age. On day 14 after administration of tannins, humoral immune response was detected against sheep red blood cells (SRBCs) by haemagglutination assay. Protective efficacy of tannins was measured against coccidial infection, induced by Eimeria species. Results revealed higher geomean titers against SRBCs in chickens administered with EOT as compared to those administered with CT and control group. Mean oocysts per gram of droppings were significantly lower (P < 0.05) in EOT administered chickens as compared to control group. Lesion scoring also showed the lowest caecal and intestinal lesion score of mild to moderate intensity in chickens administered with EOT. Further, significantly higher (P < 0.05) daily body weight gains and antibody titers were detected in EOT administered chickens as compared to those of CT administered and control groups. EOT showed the immunostimulatory properties in broilers and their administration in chickens boost the protective immunity against coccidiosis.
format Online
Article
Text
id pubmed-3919087
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-39190872014-02-26 Studies on Emblica officinalis Derived Tannins for Their Immunostimulatory and Protective Activities against Coccidiosis in Industrial Broiler Chickens Kaleem, Qari Muhammad Akhtar, Masood Awais, Mian Muhammad Saleem, Muhammad Zafar, Muddassar Iqbal, Zafar Muhammad, Faqir Anwar, Muhammad Irfan ScientificWorldJournal Research Article The present study reports the effect of Emblica officinalis (EO) derived tannins on humoral immune responses and their protective efficacy against Eimeria infection in chickens. Tannins were extracted from EO and characterized by HPLC. EO derived tannins (EOT) and commercial tannins (CT) were orally administered in broiler chicks in graded doses for three consecutive days, that is, 5th-7th days of age. On day 14 after administration of tannins, humoral immune response was detected against sheep red blood cells (SRBCs) by haemagglutination assay. Protective efficacy of tannins was measured against coccidial infection, induced by Eimeria species. Results revealed higher geomean titers against SRBCs in chickens administered with EOT as compared to those administered with CT and control group. Mean oocysts per gram of droppings were significantly lower (P < 0.05) in EOT administered chickens as compared to control group. Lesion scoring also showed the lowest caecal and intestinal lesion score of mild to moderate intensity in chickens administered with EOT. Further, significantly higher (P < 0.05) daily body weight gains and antibody titers were detected in EOT administered chickens as compared to those of CT administered and control groups. EOT showed the immunostimulatory properties in broilers and their administration in chickens boost the protective immunity against coccidiosis. Hindawi Publishing Corporation 2014-01-22 /pmc/articles/PMC3919087/ /pubmed/24578631 http://dx.doi.org/10.1155/2014/378473 Text en Copyright © 2014 Qari Muhammad Kaleem et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Kaleem, Qari Muhammad
Akhtar, Masood
Awais, Mian Muhammad
Saleem, Muhammad
Zafar, Muddassar
Iqbal, Zafar
Muhammad, Faqir
Anwar, Muhammad Irfan
Studies on Emblica officinalis Derived Tannins for Their Immunostimulatory and Protective Activities against Coccidiosis in Industrial Broiler Chickens
title Studies on Emblica officinalis Derived Tannins for Their Immunostimulatory and Protective Activities against Coccidiosis in Industrial Broiler Chickens
title_full Studies on Emblica officinalis Derived Tannins for Their Immunostimulatory and Protective Activities against Coccidiosis in Industrial Broiler Chickens
title_fullStr Studies on Emblica officinalis Derived Tannins for Their Immunostimulatory and Protective Activities against Coccidiosis in Industrial Broiler Chickens
title_full_unstemmed Studies on Emblica officinalis Derived Tannins for Their Immunostimulatory and Protective Activities against Coccidiosis in Industrial Broiler Chickens
title_short Studies on Emblica officinalis Derived Tannins for Their Immunostimulatory and Protective Activities against Coccidiosis in Industrial Broiler Chickens
title_sort studies on emblica officinalis derived tannins for their immunostimulatory and protective activities against coccidiosis in industrial broiler chickens
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919087/
https://www.ncbi.nlm.nih.gov/pubmed/24578631
http://dx.doi.org/10.1155/2014/378473
work_keys_str_mv AT kaleemqarimuhammad studiesonemblicaofficinalisderivedtanninsfortheirimmunostimulatoryandprotectiveactivitiesagainstcoccidiosisinindustrialbroilerchickens
AT akhtarmasood studiesonemblicaofficinalisderivedtanninsfortheirimmunostimulatoryandprotectiveactivitiesagainstcoccidiosisinindustrialbroilerchickens
AT awaismianmuhammad studiesonemblicaofficinalisderivedtanninsfortheirimmunostimulatoryandprotectiveactivitiesagainstcoccidiosisinindustrialbroilerchickens
AT saleemmuhammad studiesonemblicaofficinalisderivedtanninsfortheirimmunostimulatoryandprotectiveactivitiesagainstcoccidiosisinindustrialbroilerchickens
AT zafarmuddassar studiesonemblicaofficinalisderivedtanninsfortheirimmunostimulatoryandprotectiveactivitiesagainstcoccidiosisinindustrialbroilerchickens
AT iqbalzafar studiesonemblicaofficinalisderivedtanninsfortheirimmunostimulatoryandprotectiveactivitiesagainstcoccidiosisinindustrialbroilerchickens
AT muhammadfaqir studiesonemblicaofficinalisderivedtanninsfortheirimmunostimulatoryandprotectiveactivitiesagainstcoccidiosisinindustrialbroilerchickens
AT anwarmuhammadirfan studiesonemblicaofficinalisderivedtanninsfortheirimmunostimulatoryandprotectiveactivitiesagainstcoccidiosisinindustrialbroilerchickens