Interleukin-6 Signaling Drives Fibrosis in Unresolved Inflammation

Fibrosis in response to tissue damage or persistent inflammation is a pathological hallmark of many chronic degenerative diseases. By using a model of acute peritoneal inflammation, we have examined how repeated inflammatory activation promotes fibrotic tissue injury. In this context, fibrosis was s...

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Detalles Bibliográficos
Autores principales: Fielding, Ceri A., Jones, Gareth W., McLoughlin, Rachel M., McLeod, Louise, Hammond, Victoria J., Uceda, Javier, Williams, Anwen S., Lambie, Mark, Foster, Thomas L., Liao, Chia-Te, Rice, Christopher M., Greenhill, Claire J., Colmont, Chantal S., Hams, Emily, Coles, Barbara, Kift-Morgan, Ann, Newton, Zarabeth, Craig, Katherine J., Williams, John D., Williams, Geraint T., Davies, Simon J., Humphreys, Ian R., O’Donnell, Valerie B., Taylor, Philip R., Jenkins, Brendan J., Topley, Nicholas, Jones, Simon A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919204/
https://www.ncbi.nlm.nih.gov/pubmed/24412616
http://dx.doi.org/10.1016/j.immuni.2013.10.022

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