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Timing of GTP binding and hydrolysis by translation termination factor RF3

Protein synthesis in bacteria is terminated by release factors 1 or 2 (RF1/2), which, on recognition of a stop codon in the decoding site on the ribosome, promote the hydrolytic release of the polypeptide from the transfer RNA (tRNA). Subsequently, the dissociation of RF1/2 is accelerated by RF3, a...

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Detalles Bibliográficos
Autores principales: Peske, Frank, Kuhlenkoetter, Stephan, Rodnina, Marina V., Wintermeyer, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919579/
https://www.ncbi.nlm.nih.gov/pubmed/24214994
http://dx.doi.org/10.1093/nar/gkt1095

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