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Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter
Increasing evidence indicates that active DNA demethylation is involved in several processes in mammals, resulting in developmental stage-specificity and cell lineage-specificity. The recently discovered Ten-Eleven Translocation (TET) dioxygenases are accepted to be involved in DNA demethylation by...
Autores principales: | Chen, Hui, Kazemier, Hinke G, de Groote, Marloes L., Ruiters, Marcel H. J., Xu, Guo-Liang, Rots, Marianne G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919596/ https://www.ncbi.nlm.nih.gov/pubmed/24194590 http://dx.doi.org/10.1093/nar/gkt1019 |
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