Characterization of the interaction between protein Snu13p/15.5K and the Rsa1p/NUFIP factor and demonstration of its functional importance for snoRNP assembly

The yeast Snu13p protein and its 15.5K human homolog both bind U4 snRNA and box C/D snoRNAs. They also bind the Rsa1p/NUFIP assembly factor, proposed to scaffold immature snoRNPs and to recruit the Hsp90-R2TP chaperone complex. However, the nature of the Snu13p/15.5K–Rsa1p/NUFIP interaction and its...

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Detalles Bibliográficos
Autores principales: Rothé, Benjamin, Back, Régis, Quinternet, Marc, Bizarro, Jonathan, Robert, Marie-Cécile, Blaud, Magali, Romier, Christophe, Manival, Xavier, Charpentier, Bruno, Bertrand, Edouard, Branlant, Christiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919607/
https://www.ncbi.nlm.nih.gov/pubmed/24234454
http://dx.doi.org/10.1093/nar/gkt1091

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