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Telomere extension by telomerase and ALT generates variant repeats by mechanistically distinct processes

Telomeres are terminal repetitive DNA sequences on chromosomes, and are considered to comprise almost exclusively hexameric TTAGGG repeats. We have evaluated telomere sequence content in human cells using whole-genome sequencing followed by telomere read extraction in a panel of mortal cell strains...

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Detalles Bibliográficos
Autores principales:	Lee, Michael, Hills, Mark, Conomos, Dimitri, Stutz, Michael D., Dagg, Rebecca A., Lau, Loretta M.S., Reddel, Roger R., Pickett, Hilda A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919612/ https://www.ncbi.nlm.nih.gov/pubmed/24225324 http://dx.doi.org/10.1093/nar/gkt1117

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