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CRIF1 Interacting with CDK2 Regulates Bone Marrow Microenvironment-Induced G0/G1 Arrest of Leukemia Cells

BACKGROUND: To assess the level of CR6-interacting factor 1 (CRIF1), a cell cycle negative regulator, in patients with leukemia and investigate the role of CRIF1 in regulating leukemia cell cycle. METHODS: We compared the CRIF1 level in bone marrow (BM) samples from healthy and acute myeloid leukemi...

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Detalles Bibliográficos
Autores principales: Ran, Qian, Hao, Ping, Xiao, Yanni, Xiang, Lixing, Ye, Xingde, Deng, Xiaojun, Zhao, Jiang, Li, Zhongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919709/
https://www.ncbi.nlm.nih.gov/pubmed/24520316
http://dx.doi.org/10.1371/journal.pone.0085328

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