Baicalin Protects the Cardiomyocytes from ER Stress-Induced Apoptosis: Inhibition of CHOP through Induction of Endothelial Nitric Oxide Synthase

Baicalin, the main active ingredient of the Scutellaria root, exerts anti-oxidant and anti-apoptotic effects in cardiovascular diseases. However, the therapeutic mechanism of baicalin remains unknown. Cultured neonatal rat cardiomyocytes were pre-treated with baicalin (0–50 µM) for 24 h, and subsequ...

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Detalles Bibliográficos
Autores principales: Shen, Mingzhi, Wang, Lin, Yang, Guodong, Gao, Lei, Wang, Bo, Guo, Xiaowang, Zeng, Chao, Xu, Yong, Shen, Liangliang, Cheng, Ke, Xia, Yuesheng, Li, Xiumin, Wang, Haichang, Fan, Li, Wang, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919764/
https://www.ncbi.nlm.nih.gov/pubmed/24520378
http://dx.doi.org/10.1371/journal.pone.0088389

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