Expansion of Anti-Mesothelin Specific CD4(+) and CD8(+) T Cell Responses in Patients with Pancreatic Carcinoma

We aimed to assess the status of naturally occurring CD4(+) and CD8(+) T cell responses to a tumour associated antigen, Mesothelin, in patients with pancreatic carcinoma and study the effects of elevated IL-10 on Mesothelin-specific T cell responses. For that sake, short term T cell lines were gener...

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Detalles Bibliográficos
Autores principales: Chen, Yuan, Ayaru, Lakshmana, Mathew, Sanju, Morris, Emma, Pereira, Stephen P., Behboudi, Shahriar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919833/
https://www.ncbi.nlm.nih.gov/pubmed/24520352
http://dx.doi.org/10.1371/journal.pone.0088133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919833/
https://www.ncbi.nlm.nih.gov/pubmed/24520352
http://dx.doi.org/10.1371/journal.pone.0088133

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