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Suppression of angiogenesis and tumor growth in vitro and in vivo using an anti-angiopoietin-2 single-chain antibody

Hepatocellular carcinomas (HCCs) are tumors with a highly developed vascular architecture. HCC cells require access to blood vessels for growth and metastasis; therefore, the inhibition of angiogenesis represents a potential therapeutic target for HCC that may reduce the mortality and morbidity from...

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Detalles Bibliográficos
Autores principales: ZHANG, ZHONG-LIN, ZHANG, JI-FA, YUAN, YU-FENG, HE, YUE-MING, LIU, QUAN-YAN, MAO, XIAO-WEN, AI, YONG-BIAO, LIU, ZHI-SU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919851/
https://www.ncbi.nlm.nih.gov/pubmed/24520243
http://dx.doi.org/10.3892/etm.2014.1476