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Knockdown of glucose-regulated protein 78 abrogates chemoresistance of hypopharyngeal carcinoma cells to cisplatin induced by unfolded protein in response to severe hypoxia

Hypoxia renders tumor cells with reduced sensitivity and increased resistance to chemotherapeutic agents. One of the possible mechanisms underlying this unfavorable status is activation of the unfolded protein response (UPR) under hypoxic conditions, due to the upregulation of glucose-regulated prot...

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Detalles Bibliográficos
Autores principales:	PI, LIHONG, LI, XIAOMING, SONG, QI, SHEN, YUPENG, LU, XIUYING, DI, BIN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919852/ https://www.ncbi.nlm.nih.gov/pubmed/24527073 http://dx.doi.org/10.3892/ol.2013.1753

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