Cargando…

Tissue engineering is a promising method for the repair of spinal cord injuries (Review)

Spinal cord injury (SCI) may lead to a devastating and permanent loss of neurological function, which may place a great economic burden on the family of the patient and society. Methods for reducing the death of neuronal cells, inhibiting immune and inflammatory reactions, and promoting the growth o...

Descripción completa

Detalles Bibliográficos
Autores principales: JI, WENCHEN, HU, SHOUYE, ZHOU, JIAO, WANG, GANG, WANG, KUNZHENG, ZHANG, YUELIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919911/
https://www.ncbi.nlm.nih.gov/pubmed/24520240
http://dx.doi.org/10.3892/etm.2013.1454
_version_ 1782303108368433152
author JI, WENCHEN
HU, SHOUYE
ZHOU, JIAO
WANG, GANG
WANG, KUNZHENG
ZHANG, YUELIN
author_facet JI, WENCHEN
HU, SHOUYE
ZHOU, JIAO
WANG, GANG
WANG, KUNZHENG
ZHANG, YUELIN
author_sort JI, WENCHEN
collection PubMed
description Spinal cord injury (SCI) may lead to a devastating and permanent loss of neurological function, which may place a great economic burden on the family of the patient and society. Methods for reducing the death of neuronal cells, inhibiting immune and inflammatory reactions, and promoting the growth of axons in order to build up synapses with the target cells are the focus of current research. Target cells are located in the damaged spinal cord which create a connect with the scaffold. As tissue engineering technology is developed for use in a variety of different areas, particularly the biomedical field, a clear understanding of the mechanisms of tissue engineering is important. This review establishes how this technology may be used in basic experiments with regard to SCI and considers its potential future clinical use.
format Online
Article
Text
id pubmed-3919911
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher D.A. Spandidos
record_format MEDLINE/PubMed
spelling pubmed-39199112014-02-11 Tissue engineering is a promising method for the repair of spinal cord injuries (Review) JI, WENCHEN HU, SHOUYE ZHOU, JIAO WANG, GANG WANG, KUNZHENG ZHANG, YUELIN Exp Ther Med Articles Spinal cord injury (SCI) may lead to a devastating and permanent loss of neurological function, which may place a great economic burden on the family of the patient and society. Methods for reducing the death of neuronal cells, inhibiting immune and inflammatory reactions, and promoting the growth of axons in order to build up synapses with the target cells are the focus of current research. Target cells are located in the damaged spinal cord which create a connect with the scaffold. As tissue engineering technology is developed for use in a variety of different areas, particularly the biomedical field, a clear understanding of the mechanisms of tissue engineering is important. This review establishes how this technology may be used in basic experiments with regard to SCI and considers its potential future clinical use. D.A. Spandidos 2014-03 2013-12-18 /pmc/articles/PMC3919911/ /pubmed/24520240 http://dx.doi.org/10.3892/etm.2013.1454 Text en Copyright © 2014, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Articles
JI, WENCHEN
HU, SHOUYE
ZHOU, JIAO
WANG, GANG
WANG, KUNZHENG
ZHANG, YUELIN
Tissue engineering is a promising method for the repair of spinal cord injuries (Review)
title Tissue engineering is a promising method for the repair of spinal cord injuries (Review)
title_full Tissue engineering is a promising method for the repair of spinal cord injuries (Review)
title_fullStr Tissue engineering is a promising method for the repair of spinal cord injuries (Review)
title_full_unstemmed Tissue engineering is a promising method for the repair of spinal cord injuries (Review)
title_short Tissue engineering is a promising method for the repair of spinal cord injuries (Review)
title_sort tissue engineering is a promising method for the repair of spinal cord injuries (review)
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919911/
https://www.ncbi.nlm.nih.gov/pubmed/24520240
http://dx.doi.org/10.3892/etm.2013.1454
work_keys_str_mv AT jiwenchen tissueengineeringisapromisingmethodfortherepairofspinalcordinjuriesreview
AT hushouye tissueengineeringisapromisingmethodfortherepairofspinalcordinjuriesreview
AT zhoujiao tissueengineeringisapromisingmethodfortherepairofspinalcordinjuriesreview
AT wanggang tissueengineeringisapromisingmethodfortherepairofspinalcordinjuriesreview
AT wangkunzheng tissueengineeringisapromisingmethodfortherepairofspinalcordinjuriesreview
AT zhangyuelin tissueengineeringisapromisingmethodfortherepairofspinalcordinjuriesreview