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Tissue engineering is a promising method for the repair of spinal cord injuries (Review)
Spinal cord injury (SCI) may lead to a devastating and permanent loss of neurological function, which may place a great economic burden on the family of the patient and society. Methods for reducing the death of neuronal cells, inhibiting immune and inflammatory reactions, and promoting the growth o...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919911/ https://www.ncbi.nlm.nih.gov/pubmed/24520240 http://dx.doi.org/10.3892/etm.2013.1454 |
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author | JI, WENCHEN HU, SHOUYE ZHOU, JIAO WANG, GANG WANG, KUNZHENG ZHANG, YUELIN |
author_facet | JI, WENCHEN HU, SHOUYE ZHOU, JIAO WANG, GANG WANG, KUNZHENG ZHANG, YUELIN |
author_sort | JI, WENCHEN |
collection | PubMed |
description | Spinal cord injury (SCI) may lead to a devastating and permanent loss of neurological function, which may place a great economic burden on the family of the patient and society. Methods for reducing the death of neuronal cells, inhibiting immune and inflammatory reactions, and promoting the growth of axons in order to build up synapses with the target cells are the focus of current research. Target cells are located in the damaged spinal cord which create a connect with the scaffold. As tissue engineering technology is developed for use in a variety of different areas, particularly the biomedical field, a clear understanding of the mechanisms of tissue engineering is important. This review establishes how this technology may be used in basic experiments with regard to SCI and considers its potential future clinical use. |
format | Online Article Text |
id | pubmed-3919911 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-39199112014-02-11 Tissue engineering is a promising method for the repair of spinal cord injuries (Review) JI, WENCHEN HU, SHOUYE ZHOU, JIAO WANG, GANG WANG, KUNZHENG ZHANG, YUELIN Exp Ther Med Articles Spinal cord injury (SCI) may lead to a devastating and permanent loss of neurological function, which may place a great economic burden on the family of the patient and society. Methods for reducing the death of neuronal cells, inhibiting immune and inflammatory reactions, and promoting the growth of axons in order to build up synapses with the target cells are the focus of current research. Target cells are located in the damaged spinal cord which create a connect with the scaffold. As tissue engineering technology is developed for use in a variety of different areas, particularly the biomedical field, a clear understanding of the mechanisms of tissue engineering is important. This review establishes how this technology may be used in basic experiments with regard to SCI and considers its potential future clinical use. D.A. Spandidos 2014-03 2013-12-18 /pmc/articles/PMC3919911/ /pubmed/24520240 http://dx.doi.org/10.3892/etm.2013.1454 Text en Copyright © 2014, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Articles JI, WENCHEN HU, SHOUYE ZHOU, JIAO WANG, GANG WANG, KUNZHENG ZHANG, YUELIN Tissue engineering is a promising method for the repair of spinal cord injuries (Review) |
title | Tissue engineering is a promising method for the repair of spinal cord injuries (Review) |
title_full | Tissue engineering is a promising method for the repair of spinal cord injuries (Review) |
title_fullStr | Tissue engineering is a promising method for the repair of spinal cord injuries (Review) |
title_full_unstemmed | Tissue engineering is a promising method for the repair of spinal cord injuries (Review) |
title_short | Tissue engineering is a promising method for the repair of spinal cord injuries (Review) |
title_sort | tissue engineering is a promising method for the repair of spinal cord injuries (review) |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919911/ https://www.ncbi.nlm.nih.gov/pubmed/24520240 http://dx.doi.org/10.3892/etm.2013.1454 |
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