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The E. coli CNF1 as a Pioneering Therapy for the Central Nervous System Diseases
The Cytotoxic Necrotizing Factor 1 (CNF1), a protein toxin from pathogenic E. coli, modulates the Rho GTPases, thus, directing the organization of the actin cytoskeleton. In the nervous system, the Rho GTPases play a key role in several processes, controlling the morphogenesis of dendritic spines an...
Autores principales: | Travaglione, Sara, Loizzo, Stefano, Ballan, Giulia, Fiorentini, Carla, Fabbri, Alessia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920261/ https://www.ncbi.nlm.nih.gov/pubmed/24402235 http://dx.doi.org/10.3390/toxins6010270 |
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