Cargando…

Bringing dead proteins back to life

A small molecule called EMD 57033 can repair motor proteins that have stopped working as a result of stress.

Detalles Bibliográficos
Autores principales:	A Wustman, Brandon, Steele, John W, Sjoberg, Eric R, Stevens, Anthony C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2014
Materias:	Biophysics and Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920479/ https://www.ncbi.nlm.nih.gov/pubmed/24520167 http://dx.doi.org/10.7554/eLife.02189

Ejemplares similares

Problems on the back of an envelope
por: Anikeeva, Polina, et al.
Publicado: (2016)

Influenza-virus membrane fusion by cooperative fold-back of stochastically induced hemagglutinin intermediates
por: Ivanovic, Tijana, et al.
Publicado: (2013)

Life in focus
por: Dieckmann, Carol, et al.
Publicado: (2016)

C-terminal threonines and serines play distinct roles in the desensitization of rhodopsin, a G protein-coupled receptor
por: Azevedo, Anthony W, et al.
Publicado: (2015)

Encounter complexes and dimensionality reduction in protein–protein association
por: Kozakov, Dima, et al.
Publicado: (2014)

Monochromatic multicomponent fluorescence sedimentation velocity for the study of high-affinity protein interactions
por: Zhao, Huaying, et al.
Publicado: (2016)

Bacterial flagellar capping proteins adopt diverse oligomeric states
por: Postel, Sandra, et al.
Publicado: (2016)

Nanoscale protein architecture of the kidney glomerular basement membrane
por: Suleiman, Hani, et al.
Publicado: (2013)

Trifunctional cross-linker for mapping protein-protein interaction networks and comparing protein conformational states
por: Tan, Dan, et al.
Publicado: (2016)

Correction: Nanoscale protein architecture of the kidney glomerular basement membrane
por: Suleiman, Hani, et al.
Publicado: (2013)

Contacts-based prediction of binding affinity in protein–protein complexes
por: Vangone, Anna, et al.
Publicado: (2015)

Protein complexes in focus
por: Glaeser, Robert M
Publicado: (2016)

Side-binding proteins modulate actin filament dynamics
por: Crevenna, Alvaro H, et al.
Publicado: (2015)

Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction
por: Laxmikanthan, Gurunathan, et al.
Publicado: (2016)

Nucleocapsid assembly in pneumoviruses is regulated by conformational switching of the N protein
por: Renner, Max, et al.
Publicado: (2016)

Transient protein-protein interactions perturb E. coli metabolome and cause gene dosage toxicity
por: Bhattacharyya, Sanchari, et al.
Publicado: (2016)

Structural basis for the hijacking of endosomal sorting nexin proteins by Chlamydia trachomatis
por: Paul, Blessy, et al.
Publicado: (2017)

Residue proximity information and protein model discrimination using saturation-suppressor mutagenesis
por: Sahoo, Anusmita, et al.
Publicado: (2015)

Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection
por: Derebe, Mehabaw G, et al.
Publicado: (2014)

An internal thioester in a pathogen surface protein mediates covalent host binding
por: Walden, Miriam, et al.
Publicado: (2015)

Single-molecule observation of DNA compaction by meiotic protein SYCP3
por: Syrjänen, Johanna L, et al.
Publicado: (2017)

Labeling proteins inside living cells using external fluorophores for microscopy
por: Teng, Kai Wen, et al.
Publicado: (2016)

Checkpoint proteins come under scrutiny
por: Mora-Santos, Maria, et al.
Publicado: (2013)

Proteins acting out of (dis)order
por: Eliezer, David
Publicado: (2017)

Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1
por: Jia, Xiaofei, et al.
Publicado: (2014)

Labeling Proteins Inside Living Cells Using External Fluorophores for Fluorescence Microscopy
por: Teng, Kai Wen, et al.
Publicado: (2017)

Dilation of fusion pores by crowding of SNARE proteins
por: Wu, Zhenyong, et al.
Publicado: (2017)

Modelling dynamics in protein crystal structures by ensemble refinement
por: Burnley, B Tom, et al.
Publicado: (2012)

Emergence and evolution of an interaction between intrinsically disordered proteins
por: Hultqvist, Greta, et al.
Publicado: (2017)

The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding
por: Mysling, Simon, et al.
Publicado: (2016)

Structural dynamics of E. coli single-stranded DNA binding protein reveal DNA wrapping and unwrapping pathways
por: Suksombat, Sukrit, et al.
Publicado: (2015)

Looking inside the cell
por: Arakel, Eric C, et al.
Publicado: (2017)

Common intermediates and kinetics, but different energetics, in the assembly of SNARE proteins
por: Zorman, Sylvain, et al.
Publicado: (2014)

The biological function of an insect antifreeze protein simulated by molecular dynamics
por: Kuiper, Michael J, et al.
Publicado: (2015)

Probing protein flexibility reveals a mechanism for selective promiscuity
por: Pabon, Nicolas A, et al.
Publicado: (2017)

Phase transitions of multivalent proteins can promote clustering of membrane receptors
por: Banjade, Sudeep, et al.
Publicado: (2014)

Recognition of the small regulatory RNA RydC by the bacterial Hfq protein
por: Dimastrogiovanni, Daniela, et al.
Publicado: (2014)

Pre-transition effects mediate forces of assembly between transmembrane proteins
por: Katira, Shachi, et al.
Publicado: (2016)

Mapping out Min protein patterns in fully confined fluidic chambers
por: Caspi, Yaron, et al.
Publicado: (2016)

Single-protein detection in crowded molecular environments in cryo-EM images
por: Rickgauer, J Peter, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_v70e6je31olk66bi5laidgn3hq