Is Radiosensitivity Associated to Different Types of Blood Groups? (A cytogenetic study)

Many biological factors affect radiosensitivity. In this study, radiosensitivity among the different blood groups was investigated. Peripheral blood sample of 95 healthy people were divided into two parts. One part was irradiated with 2 Gy Co-60 gamma rays and the second one was considered as contro...

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Detalles Bibliográficos
Autores principales: Elahimanesh, Farideh, Shabestani Monfared, Ali, Khosravifarsani, Meysam, Akhavan Niaki, Haleh, Abedian, Zeinab, Hajian-Tilaki, Karimollah, Borzouisileh, Sajad, Seyfizadeh, Nayer, Amiri, Mehrangiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Babol University of Medical Sciences 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920532/
https://www.ncbi.nlm.nih.gov/pubmed/24551803
Descripción
Sumario:Many biological factors affect radiosensitivity. In this study, radiosensitivity among the different blood groups was investigated. Peripheral blood sample of 95 healthy people were divided into two parts. One part was irradiated with 2 Gy Co-60 gamma rays and the second one was considered as control. Then all the samples were studied by cytokinesis-blocked micronucleus assay (CBMN assay). Our study showed that the radiosensitivity index of A+ and O+ groups was significantly higher and lower than other blood groups, respectively. It seems that blood type can be used as a radiosensitivity index for determining the given dose to radiotherapy, although extensive studies are necessary.

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