Is Radiosensitivity Associated to Different Types of Blood Groups? (A cytogenetic study)

Many biological factors affect radiosensitivity. In this study, radiosensitivity among the different blood groups was investigated. Peripheral blood sample of 95 healthy people were divided into two parts. One part was irradiated with 2 Gy Co-60 gamma rays and the second one was considered as contro...

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Autores principales: Elahimanesh, Farideh, Shabestani Monfared, Ali, Khosravifarsani, Meysam, Akhavan Niaki, Haleh, Abedian, Zeinab, Hajian-Tilaki, Karimollah, Borzouisileh, Sajad, Seyfizadeh, Nayer, Amiri, Mehrangiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Babol University of Medical Sciences 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920532/
https://www.ncbi.nlm.nih.gov/pubmed/24551803
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author Elahimanesh, Farideh
Shabestani Monfared, Ali
Khosravifarsani, Meysam
Akhavan Niaki, Haleh
Abedian, Zeinab
Hajian-Tilaki, Karimollah
Borzouisileh, Sajad
Seyfizadeh, Nayer
Amiri, Mehrangiz
author_facet Elahimanesh, Farideh
Shabestani Monfared, Ali
Khosravifarsani, Meysam
Akhavan Niaki, Haleh
Abedian, Zeinab
Hajian-Tilaki, Karimollah
Borzouisileh, Sajad
Seyfizadeh, Nayer
Amiri, Mehrangiz
author_sort Elahimanesh, Farideh
collection PubMed
description Many biological factors affect radiosensitivity. In this study, radiosensitivity among the different blood groups was investigated. Peripheral blood sample of 95 healthy people were divided into two parts. One part was irradiated with 2 Gy Co-60 gamma rays and the second one was considered as control. Then all the samples were studied by cytokinesis-blocked micronucleus assay (CBMN assay). Our study showed that the radiosensitivity index of A+ and O+ groups was significantly higher and lower than other blood groups, respectively. It seems that blood type can be used as a radiosensitivity index for determining the given dose to radiotherapy, although extensive studies are necessary.
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spelling pubmed-39205322014-02-18 Is Radiosensitivity Associated to Different Types of Blood Groups? (A cytogenetic study) Elahimanesh, Farideh Shabestani Monfared, Ali Khosravifarsani, Meysam Akhavan Niaki, Haleh Abedian, Zeinab Hajian-Tilaki, Karimollah Borzouisileh, Sajad Seyfizadeh, Nayer Amiri, Mehrangiz Int J Mol Cell Med Original Article Many biological factors affect radiosensitivity. In this study, radiosensitivity among the different blood groups was investigated. Peripheral blood sample of 95 healthy people were divided into two parts. One part was irradiated with 2 Gy Co-60 gamma rays and the second one was considered as control. Then all the samples were studied by cytokinesis-blocked micronucleus assay (CBMN assay). Our study showed that the radiosensitivity index of A+ and O+ groups was significantly higher and lower than other blood groups, respectively. It seems that blood type can be used as a radiosensitivity index for determining the given dose to radiotherapy, although extensive studies are necessary. Babol University of Medical Sciences 2013 /pmc/articles/PMC3920532/ /pubmed/24551803 Text en © 2013, International Journal of Molecular and Cellular Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Elahimanesh, Farideh
Shabestani Monfared, Ali
Khosravifarsani, Meysam
Akhavan Niaki, Haleh
Abedian, Zeinab
Hajian-Tilaki, Karimollah
Borzouisileh, Sajad
Seyfizadeh, Nayer
Amiri, Mehrangiz
Is Radiosensitivity Associated to Different Types of Blood Groups? (A cytogenetic study)
title Is Radiosensitivity Associated to Different Types of Blood Groups? (A cytogenetic study)
title_full Is Radiosensitivity Associated to Different Types of Blood Groups? (A cytogenetic study)
title_fullStr Is Radiosensitivity Associated to Different Types of Blood Groups? (A cytogenetic study)
title_full_unstemmed Is Radiosensitivity Associated to Different Types of Blood Groups? (A cytogenetic study)
title_short Is Radiosensitivity Associated to Different Types of Blood Groups? (A cytogenetic study)
title_sort is radiosensitivity associated to different types of blood groups? (a cytogenetic study)
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920532/
https://www.ncbi.nlm.nih.gov/pubmed/24551803
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