Cargando…

The TCR ligand-inducible expression of CD73 marks γδ lineage commitment and a metastable intermediate in effector specification

Numerous studies indicate that γδ T cell receptor (γδTCR) expression alone does not reliably mark commitment of early thymic progenitors to the γδ fate. This raises the possibility that the γδTCR is unable to intrinsically specify fate and instead requires additional environmental factors, including...

Descripción completa

Detalles Bibliográficos
Autores principales: Coffey, Francis, Lee, Sang-Yun, Buus, Terkild B., Lauritsen, Jens-Peter Holst, Wong, Gladys W., Joachims, Michelle L., Thompson, Linda F., Zúñiga-Pflücker, Juan Carlos, Kappes, Dietmar J., Wiest, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920555/
https://www.ncbi.nlm.nih.gov/pubmed/24493796
http://dx.doi.org/10.1084/jem.20131540

Ejemplares similares