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Gata3 drives development of RORγt(+) group 3 innate lymphoid cells

Group 3 innate lymphoid cells (ILC3) include IL-22–producing NKp46(+) cells and IL-17A/IL-22–producing CD4(+) lymphoid tissue inducerlike cells that express RORγt and are implicated in protective immunity at mucosal surfaces. Whereas the transcription factor Gata3 is essential for T cell and ILC2 de...

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Detalles Bibliográficos
Autores principales:	Serafini, Nicolas, Klein Wolterink, Roel G.J., Satoh-Takayama, Naoko, Xu, Wei, Vosshenrich, Christian A.J., Hendriks, Rudi W., Di Santo, James P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2014
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920560/ https://www.ncbi.nlm.nih.gov/pubmed/24419270 http://dx.doi.org/10.1084/jem.20131038

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