Pituitary adenylate cyclase-activating polypeptide (PACAP) inhibits the slow afterhyperpolarizing current sI(AHP) in CA1 pyramidal neurons by activating multiple signaling pathways

The slow afterhyperpolarizing current (sI(AHP)) is a calcium-dependent potassium current that underlies the late phase of spike frequency adaptation in hippocampal and neocortical neurons. sI(AHP) is a well-known target of modulation by several neurotransmitters acting via the cyclic AMP (cAMP) and...

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Detalles Bibliográficos
Autores principales: Taylor, Ruth DT, Madsen, Marita Grønning, Krause, Michael, Sampedro-Castañeda, Marisol, Stocker, Martin, Pedarzani, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY PERIODICALS, INC 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920641/
https://www.ncbi.nlm.nih.gov/pubmed/23996525
http://dx.doi.org/10.1002/hipo.22201

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