Cargando…
Large conserved domains of low DNA methylation maintained by Dnmt3a
Gains and losses in DNA methylation are prominent features of mammalian cell types. To gain insight into mechanisms that could promote shifts in DNA methylation and contribute to cell fate changes, including malignant transformation, we performed genome-wide mapping of 5-methylcytosine and 5-hydroxy...
Autores principales: | Jeong, Mira, Sun, Deqiang, Luo, Min, Huang, Yun, Challen, Grant A., Rodriguez, Benjamin, Zhang, Xiaotian, Chavez, Lukas, Wang, Hui, Hannah, Rebecca, Kim, Sang-Bae, Yang, Liubin, Ko, Myunggon, Chen, Rui, Göttgens, Berthold, Lee, Ju-Seog, Gunaratne, Preethi, Godley, Lucy A., Darlington, Gretchen J., Rao, Anjana, Li, Wei, Goodell, Margaret A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920905/ https://www.ncbi.nlm.nih.gov/pubmed/24270360 http://dx.doi.org/10.1038/ng.2836 |
Ejemplares similares
-
DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells
por: Zhang, Xiaotian, et al.
Publicado: (2016) -
Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo
por: Jeong, Mira, et al.
Publicado: (2018) -
Acute loss of TET function results in aggressive myeloid cancer in mice
por: An, Jungeun, et al.
Publicado: (2015) -
DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A
por: Huang, Yung-Hsin, et al.
Publicado: (2017) -
Promiscuous Expression of H2B-GFP Transgene in Hematopoietic Stem Cells
por: Challen, Grant A., et al.
Publicado: (2008)