SYK Allelic Loss and the Role of Syk-Regulated Genes in Breast Cancer Survival

Heterozygotic loss of SYK, a non-receptor tyrosine kinase, gives rise to mouse mammary tumor formation where Syk protein levels are reduced by about half; loss of SYK mRNA is correlated with invasive cell behavior in in vitro models; and SYK loss has been correlated with distant metastases in patien...

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Detalles Bibliográficos
Autores principales: Blancato, Jan, Graves, Ashley, Rashidi, Banafsheh, Moroni, Maria, Tchobe, Leopold, Ozdemirli, Metin, Kallakury, Bhaskar, Makambi, Kepher H., Marian, Catalin, Mueller, Susette C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921124/
https://www.ncbi.nlm.nih.gov/pubmed/24523870
http://dx.doi.org/10.1371/journal.pone.0087610

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