BRK Targets Dok1 for Ubiquitin-Mediated Proteasomal Degradation to Promote Cell Proliferation and Migration

Breast tumor kinase (BRK), also known as protein tyrosine kinase 6 (PTK6), is a non-receptor tyrosine kinase overexpressed in more that 60% of human breast carcinomas. The overexpression of BRK has been shown to sensitize mammary epithelial cells to mitogenic signaling and to promote cell proliferat...

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Detalles Bibliográficos
Autores principales: Miah, Sayem, Goel, Raghuveera Kumar, Dai, Chenlu, Kalra, Natasha, Beaton-Brown, Erika, Bagu, Edward T., Bonham, Keith, Lukong, Kiven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921129/
https://www.ncbi.nlm.nih.gov/pubmed/24523872
http://dx.doi.org/10.1371/journal.pone.0087684

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