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Impact of STAT1 and CD8(+) T cells on the antineoplastic activity of lapatinib and doxorubicin against spontaneous mammary tumors
We have recently demonstrated that CD8(+) T cells provide a critical contribution to the antineoplastic activity of 2 chemotherapeutic agents, i.e., doxorubicin and lapatinib, in a model of spontaneous mammary carcinogenesis. The activation of CD8(+) T cells and their recruitment to neoplastic lesio...
Autores principales: | Tymoszuk, Piotr, Doppler, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921202/ https://www.ncbi.nlm.nih.gov/pubmed/24527364 http://dx.doi.org/10.4161/onci.26689 |
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