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NSS for an RCC in a patient with renal insufficiency after heart transplant because of right ventricular tumor

The effect of the immunosuppressive therapy on the development of neoplasms has become the object of an ever increasing interest for clinicians all over the world. The literature on neoplasms development in the course of therapy following transplants has confirmed a considerable increase in the inci...

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Autores principales: Prokopowicz, Grzegorz, Życzkowski, Marcin, Nowakowski, Krzysztof, Bryniarski, Piotr, Paradysz, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Polish Urological Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921851/
https://www.ncbi.nlm.nih.gov/pubmed/24578985
http://dx.doi.org/10.5173/ceju.2013.01.art11
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author Prokopowicz, Grzegorz
Życzkowski, Marcin
Nowakowski, Krzysztof
Bryniarski, Piotr
Paradysz, Andrzej
author_facet Prokopowicz, Grzegorz
Życzkowski, Marcin
Nowakowski, Krzysztof
Bryniarski, Piotr
Paradysz, Andrzej
author_sort Prokopowicz, Grzegorz
collection PubMed
description The effect of the immunosuppressive therapy on the development of neoplasms has become the object of an ever increasing interest for clinicians all over the world. The literature on neoplasms development in the course of therapy following transplants has confirmed a considerable increase in the incidence of neoplasms of the skin and lymph nodes. Organ neoplasms developing in patients after transplants are characterized by increased progression, poor cellular diversification and a more unfavorable prognosis than in the general population The aim of the study is to present the case of a nephron–sparing surgery of a renal tumor (NSS) without any intraoperative ischaemia in a 55–year–old female patient with an orthotopic heart transplant and renal insufficiency following a prolonged immune suppression. It is estimated that the patients at the highest risk of neoplasm development are those in the first months after transplant, especially heart transplant. They require maximum doses of immunosuppressive drugs. In the case of patients with initial renal insufficiency the duration of ischaemia of the organ operated on should be minimized, and if possible, surgery should be conducted without clamping the renal pedicle. The surgical treatment of RCC (renal cell carcinoma) in transplant patients does not require any reduction in the amount of the immunosuppressive drugs.
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spelling pubmed-39218512014-02-27 NSS for an RCC in a patient with renal insufficiency after heart transplant because of right ventricular tumor Prokopowicz, Grzegorz Życzkowski, Marcin Nowakowski, Krzysztof Bryniarski, Piotr Paradysz, Andrzej Cent European J Urol Case Report The effect of the immunosuppressive therapy on the development of neoplasms has become the object of an ever increasing interest for clinicians all over the world. The literature on neoplasms development in the course of therapy following transplants has confirmed a considerable increase in the incidence of neoplasms of the skin and lymph nodes. Organ neoplasms developing in patients after transplants are characterized by increased progression, poor cellular diversification and a more unfavorable prognosis than in the general population The aim of the study is to present the case of a nephron–sparing surgery of a renal tumor (NSS) without any intraoperative ischaemia in a 55–year–old female patient with an orthotopic heart transplant and renal insufficiency following a prolonged immune suppression. It is estimated that the patients at the highest risk of neoplasm development are those in the first months after transplant, especially heart transplant. They require maximum doses of immunosuppressive drugs. In the case of patients with initial renal insufficiency the duration of ischaemia of the organ operated on should be minimized, and if possible, surgery should be conducted without clamping the renal pedicle. The surgical treatment of RCC (renal cell carcinoma) in transplant patients does not require any reduction in the amount of the immunosuppressive drugs. Polish Urological Association 2013-04-26 2013 /pmc/articles/PMC3921851/ /pubmed/24578985 http://dx.doi.org/10.5173/ceju.2013.01.art11 Text en Copyright by Polish Urological Association http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Prokopowicz, Grzegorz
Życzkowski, Marcin
Nowakowski, Krzysztof
Bryniarski, Piotr
Paradysz, Andrzej
NSS for an RCC in a patient with renal insufficiency after heart transplant because of right ventricular tumor
title NSS for an RCC in a patient with renal insufficiency after heart transplant because of right ventricular tumor
title_full NSS for an RCC in a patient with renal insufficiency after heart transplant because of right ventricular tumor
title_fullStr NSS for an RCC in a patient with renal insufficiency after heart transplant because of right ventricular tumor
title_full_unstemmed NSS for an RCC in a patient with renal insufficiency after heart transplant because of right ventricular tumor
title_short NSS for an RCC in a patient with renal insufficiency after heart transplant because of right ventricular tumor
title_sort nss for an rcc in a patient with renal insufficiency after heart transplant because of right ventricular tumor
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921851/
https://www.ncbi.nlm.nih.gov/pubmed/24578985
http://dx.doi.org/10.5173/ceju.2013.01.art11
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