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Comparing Electrolytes in Prestorage Leukocyte-Reduced Packed Cell versus Unfiltered Packed Cell
BACKGROUND: Blood transfusion is associated with side effects caused by residual leukocytes in blood and blood components. Using leukodepleted blood components can decrease some of these adverse effects. Among the various methods to remove leukocytes in blood components, prestorage leukoreduction ha...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shahid Sadoughi University of Medical Sciences
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921877/ https://www.ncbi.nlm.nih.gov/pubmed/24575277 |
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author | Fallahi, L Ghiliyan, R Hashemi, A Fatemi, A Saeedi, M |
author_facet | Fallahi, L Ghiliyan, R Hashemi, A Fatemi, A Saeedi, M |
author_sort | Fallahi, L |
collection | PubMed |
description | BACKGROUND: Blood transfusion is associated with side effects caused by residual leukocytes in blood and blood components. Using leukodepleted blood components can decrease some of these adverse effects. Among the various methods to remove leukocytes in blood components, prestorage leukoreduction has been most efficient, but the evidence of clinical side effects awaits further studies. We evaluated changes of electrolytes in prestorage leukocyte-reduced red blood cells. MATERIALS AND METHODS: In this case-control study, one hundred twenty eight packed cells were studied: 64 unfiltered packed cells and 64 prestorage filtered packed cell. Two groups were matched as sex and age. Electrolytes such as Calcium, Sodium, and Potassium of two groups were measured, and compared during preparation. RESULTS: In this study, mean of Calcium in unfiltered and filtered group were 6.16±1.09 mg/dl and 5.57±2.21 mg/dl, respectively (P-value<0.055). Mean of Sodium in unfiltered group also was 155.91+/-9.51meq/l and in filtered group, 153.05+/-13.21meq/l (P-value<0.163), and mean of Potassium in unfiltered group was 5.01+/-1.72 meq/l and in filtered group, 7.42+/-2.45meq/l (P-value<0.001). CONCLUSION: Releasing of Potassium during preparation of prestorage leukoreduction can cause increased Potassium level and hemoglobin concentration changes in prestorage filtered packed cell. |
format | Online Article Text |
id | pubmed-3921877 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Shahid Sadoughi University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-39218772014-02-26 Comparing Electrolytes in Prestorage Leukocyte-Reduced Packed Cell versus Unfiltered Packed Cell Fallahi, L Ghiliyan, R Hashemi, A Fatemi, A Saeedi, M Iran J Ped Hematol Oncol Original Article BACKGROUND: Blood transfusion is associated with side effects caused by residual leukocytes in blood and blood components. Using leukodepleted blood components can decrease some of these adverse effects. Among the various methods to remove leukocytes in blood components, prestorage leukoreduction has been most efficient, but the evidence of clinical side effects awaits further studies. We evaluated changes of electrolytes in prestorage leukocyte-reduced red blood cells. MATERIALS AND METHODS: In this case-control study, one hundred twenty eight packed cells were studied: 64 unfiltered packed cells and 64 prestorage filtered packed cell. Two groups were matched as sex and age. Electrolytes such as Calcium, Sodium, and Potassium of two groups were measured, and compared during preparation. RESULTS: In this study, mean of Calcium in unfiltered and filtered group were 6.16±1.09 mg/dl and 5.57±2.21 mg/dl, respectively (P-value<0.055). Mean of Sodium in unfiltered group also was 155.91+/-9.51meq/l and in filtered group, 153.05+/-13.21meq/l (P-value<0.163), and mean of Potassium in unfiltered group was 5.01+/-1.72 meq/l and in filtered group, 7.42+/-2.45meq/l (P-value<0.001). CONCLUSION: Releasing of Potassium during preparation of prestorage leukoreduction can cause increased Potassium level and hemoglobin concentration changes in prestorage filtered packed cell. Shahid Sadoughi University of Medical Sciences 2013 2013-07-22 /pmc/articles/PMC3921877/ /pubmed/24575277 Text en © 2013: Iranian Journal of Pediatric Hematology Oncology This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Fallahi, L Ghiliyan, R Hashemi, A Fatemi, A Saeedi, M Comparing Electrolytes in Prestorage Leukocyte-Reduced Packed Cell versus Unfiltered Packed Cell |
title | Comparing Electrolytes in Prestorage Leukocyte-Reduced Packed Cell versus Unfiltered Packed Cell |
title_full | Comparing Electrolytes in Prestorage Leukocyte-Reduced Packed Cell versus Unfiltered Packed Cell |
title_fullStr | Comparing Electrolytes in Prestorage Leukocyte-Reduced Packed Cell versus Unfiltered Packed Cell |
title_full_unstemmed | Comparing Electrolytes in Prestorage Leukocyte-Reduced Packed Cell versus Unfiltered Packed Cell |
title_short | Comparing Electrolytes in Prestorage Leukocyte-Reduced Packed Cell versus Unfiltered Packed Cell |
title_sort | comparing electrolytes in prestorage leukocyte-reduced packed cell versus unfiltered packed cell |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921877/ https://www.ncbi.nlm.nih.gov/pubmed/24575277 |
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