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Natural Killer Cells and Neuroblastoma: Tumor Recognition, Escape Mechanisms, and Possible Novel Immunotherapeutic Approaches

Neuroblastoma (NB) is the most common extra-cranial solid tumor of childhood and arises from developing sympathetic nervous system. Most primary tumors localize in the abdomen, the adrenal gland, or lumbar sympathetic ganglia. Amplification in tumor cells of MYCN, the major oncogenic driver, patient...

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Detalles Bibliográficos
Autores principales: Bottino, Cristina, Dondero, Alessandra, Bellora, Francesca, Moretta, Lorenzo, Locatelli, Franco, Pistoia, Vito, Moretta, Alessandro, Castriconi, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921882/
https://www.ncbi.nlm.nih.gov/pubmed/24575100
http://dx.doi.org/10.3389/fimmu.2014.00056