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A 4-week Repeated Dose Toxicity Study of Glycine in Rats by Gavage Administration

In order to examine the toxicity profile of glycine, an authorized food additive, a solution of glycine in water for injection was administered orally (via gavage) to male SD rats (Crl:CD(SD)) once daily for 4 weeks at doses of 500, 1000 and 2000 mg/kg/day in a volume of 10 mL/kg. Control animals re...

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Detalles Bibliográficos
Autores principales: Shibui, Yusuke, Miwa, Tadashi, Yamashita, Mayumi, Chin, Keigi, Kodama, Terutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921923/
https://www.ncbi.nlm.nih.gov/pubmed/24526813
http://dx.doi.org/10.1293/tox.2013-0026