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Anti-idiotypic antibodies reduce efficacy of the attenuated vaccine against highly pathogenic PRRSV challenge

BACKGROUND: The inability of current vaccines to provide effective protection against porcine reproductive and respiratory syndrome virus (PRRSV) infection is not fully understood. One of the reasons might be the presence of anti-idiotypic antibodies (Ab2s) to the envelope glycoprotein GP5 induced b...

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Detalles Bibliográficos
Autores principales: Yu, Ying, Cai, Xuehui, Wang, Gang, Kong, Ning, Liu, Yonggang, Xiao, Yihong, Zhang, Chong, Mu, Yang, Xiao, Shuqi, Zhao, Qin, Wang, Chengbao, Zhang, Gaiping, Hiscox, Julian A, Zhou, En-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921987/
https://www.ncbi.nlm.nih.gov/pubmed/24507659
http://dx.doi.org/10.1186/1746-6148-10-39