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Generation and Characterization of Recombinant Influenza A(H1N1) Viruses Resistant to Neuraminidase Inhibitors

OBJECTIVES: To examine the effect of neuraminidase (NA) mutations on the NA inhibitor (NAI) resistance phenotype, the recombinant influenza A/Chungbuk/4448/2008(H1N1) virus isolated in South Korea during the 2008–2009 season was generated by reverse genetics. METHODS: Site-directed mutagenesis was i...

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Detalles Bibliográficos
Autores principales:	Choi, WooYoung, Shin, Jin-Young, Jeong, Hwan-Eui, Jeong, Mi-Jin, Kim, Su-Jin, Lee, Joo-Yeon, Kang, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922101/ https://www.ncbi.nlm.nih.gov/pubmed/24524021 http://dx.doi.org/10.1016/j.phrp.2013.10.005

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