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RamA, which controls expression of the MDR efflux pump AcrAB-TolC, is regulated by the Lon protease

OBJECTIVES: RamA regulates the AcrAB-TolC multidrug efflux system. Using Salmonella Typhimurium, we investigated the stability of RamA and its impact on antibiotic resistance. METHODS: To detect RamA, we introduced ramA::3XFLAG::aph into plasmid pACYC184 and transformed this into Salmonella Typhimur...

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Detalles Bibliográficos
Autores principales:	Ricci, Vito, Blair, Jessica M. A., Piddock, Laura J. V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922155/ https://www.ncbi.nlm.nih.gov/pubmed/24169580 http://dx.doi.org/10.1093/jac/dkt432

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