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Differential roles of tryptophan residues in conformational stability of Porphyromonas gingivalis HmuY hemophore

BACKGROUND: We have previously shown that the P. gingivalis HmuY hemophore-like protein binds heme and scavenges heme from host hemoproteins to further deliver it to the cognate heme receptor HmuR. The aim of this study was to characterize structural features of HmuY variants in the presence and abs...

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Detalles Bibliográficos
Autores principales: Bielecki, Marcin, Wójtowicz, Halina, Olczak, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922309/
https://www.ncbi.nlm.nih.gov/pubmed/24512694
http://dx.doi.org/10.1186/1471-2091-15-2