NSAIDS inhibit in vitro MSC chondrogenesis but not osteogenesis: implications for mechanism of bone formation inhibition in man

The non-steroidal anti-inflammatory drugs (NSAIDs) are widely used for analgesia but may inhibit bone formation. We investigated whether the reported NSAID effect on bone is related to inhibition of bone marrow mesenchymal stem cell (MSC) proliferation and osteogenic and chondrogenic differentiation...

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Detalles Bibliográficos
Autores principales: Pountos, Ippokratis, Giannoudis, Peter V, Jones, Elena, English, Anne, Churchman, Sarah, Field, Sarah, Ponchel, Frederique, Bird, Howard, Emery, Paul, McGonagle, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922374/
https://www.ncbi.nlm.nih.gov/pubmed/20070439
http://dx.doi.org/10.1111/j.1582-4934.2010.01006.x

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