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Combinatorial interference of toll-like receptor 2 and 4 synergistically stabilizes atherosclerotic plaque in apolipoprotein E-knockout mice

To test the hypothesis that combinatorial interference of toll-like receptor 2 (TLR2) and TLR4 is superior to isolated interference of TLR2 or TLR4 in stabilizing atherosclerotic plaques, lentiviruses carrying small interfering RNA of TLR2 or TLR4 were constructed and proved efficacious for knocking...

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Detalles Bibliográficos
Autores principales: Yang, Jian Min, Wang, Yan, Qi, Li Hang, Wang, Ying, Gao, Fei, Ding, Shi Fang, Ni, Mei, Liu, Chun Xi, Zhang, Cheng, Zhang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922382/
https://www.ncbi.nlm.nih.gov/pubmed/20132416
http://dx.doi.org/10.1111/j.1582-4934.2010.01028.x

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