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ESR1 gene promoter region methylation in free circulating DNA and its correlation with estrogen receptor protein expression in tumor tissue in breast cancer patients

BACKGROUND: Tumor expression of estrogen receptor (ER) is an important marker of prognosis, and is predictive of response to endocrine therapy in breast cancer. Several studies have observed that epigenetic events, such methylation of cytosines and deacetylation of histones, are involved in the comp...

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Detalles Bibliográficos
Autores principales: Martínez-Galán, Joaquina, Torres-Torres, Blanca, Núñez, María Isabel, López-Peñalver, Jesús, Del Moral, Rosario, Ruiz De Almodóvar, José Mariano, Menjón, Salomón, Concha, Ángel, Chamorro, Clara, Ríos, Sandra, Delgado, Juan Ramón
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922625/
https://www.ncbi.nlm.nih.gov/pubmed/24495356
http://dx.doi.org/10.1186/1471-2407-14-59

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