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ESR1 gene promoter region methylation in free circulating DNA and its correlation with estrogen receptor protein expression in tumor tissue in breast cancer patients
BACKGROUND: Tumor expression of estrogen receptor (ER) is an important marker of prognosis, and is predictive of response to endocrine therapy in breast cancer. Several studies have observed that epigenetic events, such methylation of cytosines and deacetylation of histones, are involved in the comp...
Autores principales: | Martínez-Galán, Joaquina, Torres-Torres, Blanca, Núñez, María Isabel, López-Peñalver, Jesús, Del Moral, Rosario, Ruiz De Almodóvar, José Mariano, Menjón, Salomón, Concha, Ángel, Chamorro, Clara, Ríos, Sandra, Delgado, Juan Ramón |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922625/ https://www.ncbi.nlm.nih.gov/pubmed/24495356 http://dx.doi.org/10.1186/1471-2407-14-59 |
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