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Inferring clonal evolution of tumors from single nucleotide somatic mutations

BACKGROUND: High-throughput sequencing allows the detection and quantification of frequencies of somatic single nucleotide variants (SNV) in heterogeneous tumor cell populations. In some cases, the evolutionary history and population frequency of the subclonal lineages of tumor cells present in the...

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Detalles Bibliográficos
Autores principales:	Jiao, Wei, Vembu, Shankar, Deshwar, Amit G, Stein, Lincoln, Morris, Quaid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922638/ https://www.ncbi.nlm.nih.gov/pubmed/24484323 http://dx.doi.org/10.1186/1471-2105-15-35

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