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A novel domain of caveolin-2 that controls nuclear targeting: regulation of insulin-specific ERK activation and nuclear translocation by caveolin-2

Herein, we report that insulin-activated extracellular signal-regulated kinase (ERK) is translocated to the nuclear envelope by caveolin-2 (cav-2) and associates with lamin A/C in the inner nuclear membrane in response to insulin. We identified that the Ser(154)–Val(155)–Ser(156) domain on the C-ter...

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Detalles Bibliográficos
Autores principales: Kwon, Hayeong, Jeong, Kyuho, Hwang, Eun Mi, Park, Jae-Yong, Pak, Yunbae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922675/
https://www.ncbi.nlm.nih.gov/pubmed/20455999
http://dx.doi.org/10.1111/j.1582-4934.2010.01079.x

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