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Suppression of NAD(P)H-quinone oxidoreductase 1 enhanced the susceptibility of cholangiocarcinoma cells to chemotherapeutic agents

BACKGROUND: Cholangiocarcinoma (CCA) is highly resistant to most of the known chemotherapeutic treatments. NAD(P)H-quinone oxidoreductase 1 (NQO1) is an antioxidant/detoxifying enzyme recently recognized as an important contributor to chemoresistance in some human cancers. However, the contribution...

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Detalles Bibliográficos
Autores principales:	Zeekpudsa, Ponsilp, Kukongviriyapan, Veerapol, Senggunprai, Laddawan, Sripa, Banchob, Prawan, Auemduan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922744/ https://www.ncbi.nlm.nih.gov/pubmed/24460787 http://dx.doi.org/10.1186/1756-9966-33-11

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